Isotopically Labeled Compounds
Medchemexpress LLC Posaconazole-d5 | 1217785-83-5 | MFCD11977890 | 99.1% | 705.81 | 5 MG
Posaconazole-d5 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second-generation, triazole compound with antifungal activity.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC DL-Alanine-d3 | 53795-94-1 | 5 MG
DL-Alanine-d3 is a deuterium labeled DL-Alanine, an amino acid that functions as the racemic compound of L- and D-alanine. It is intended for research use only. This compound serves as a tracer and an internal standard for quantitative analysis methods like NMR, GC-MS, or LC-MS. Deuteration, in this context, is noted for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Employed as a reducing and capping agent with silver nitrate aqueous solutions for nanoparticle production
- Can be utilized for researching transition metals chelation, including Cu(II), Zn(II), and Cd(II)
- Functions as a sweetener, classified alongside glycine and sodium saccharin
- Plays a crucial role in the glucose-alanine cycle between tissues and the liver
Revvity Health Sciences Inc OptiScint 14C Quench Standards, 20 mL Vial
OptiScint 14C Quench Standards, 20 mL Vial
Revvity Health Sciences Inc Phosphorus-32 Radionuclide, 1mCi (37 MBq), Specific Activity: 900-1100mCi (33.3-40.7GBq)/mmol, Monopotassium Phosphate In 1mL Water
Phosphorus-32 Radionuclide, 1mCi (37 MBq), Specific Activity: 900-1100mCi (33.3-40.7GBq)/mmol, Monopotassium Phosphate In 1mL Water
Medchemexpress LLC Amiodarone-d10 hydrochloride | 1261393-77-4 | 98.8% | C25H20D10ClI2NO3 | 1 MG
Amiodarone-d10 hydrochloride is a deuterium-labeled form of Amiodarone, an antiarrhythmic agent known for inhibiting ATP-sensitive potassium channels. It can serve as a tracer and internal standard for quantitative analysis using techniques like NMR, GC-MS, or LC-MS. Deuteration of drug molecules is being studied for its potential to impact pharmacokinetic and metabolic profiles.
- Deuterium labeled antiarrhythmic agent
- Inhibits ATP-sensitive potassium channel
- Used as a tracer and internal standard for quantitative analysis
- Potential to influence pharmacokinetic and metabolic profiles
Medchemexpress LLC Stearic acid-d35 | 17660-51-4 | 99.9% | 25 MG
Stearic acid-d35 is the deuterium labeled Stearic acid, a long chain dietary saturated fatty acid found in many animal and vegetable fats and oils. Deuteration, the incorporation of stable heavy isotopes into drug molecules, has garnered attention for its potential to influence pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC α-D-Xylose | 6763-34-4 | 150.13 | 500 G
α-D-Xylose, also known as α-D-Xylopyranose, is an endogenous metabolite and a basic component of the five-carbon fraction of biomass. It acts as a precursor of hemicellulose and participates in various enzyme-catalyzed reactions within metabolic pathways. This compound is also utilized in industries such as tanning and dyeing, and it finds application as a diabetic food.
- Basic component of biomass five-carbon fraction
- Precursor of hemicellulose
- Participates in enzyme-catalyzed reactions and metabolic pathways
- Used in tanning, dyeing, and as a diabetic food
- Appears as a solid, white to off-white substance
- Functions as an endogenous metabolite
Cayman Chemical DopamIn-d4hydrochlorIde 5mg
An internal standard for the quantification of dopamine by GC- or LC-MS
Medchemexpress LLC Isovaleric acid-d7 | 1219805-32-9 | 99.5% | 109.17 | 10 MG
Isovaleric acid-d7 is the deuterium labeled isovaleric acid. Isovaleric acid is a natural fatty acid and is known to affect neonatal death and possible Jamaican vomiting sickness in humans.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Carboplatin-d4 | 41575-94-4 | 99.0% | 375.28 | 1 MG
Carboplatin-d4 is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor that binds to DNA, inhibits replication and transcription, and induces cell death. It is a derivative of CDDP and a potent anti-cancer agent. Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Dimethyl fumarate-d2 | 23057-98-9 | 98.2% | 146.14 | 5 MG
Dimethyl fumarate-d2 is the deuterium labeled Dimethyl fumarate. Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Amitraz-d3 | 33089-61-1 | 99.5% | 5 MG
Amitraz-d3 is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC CER10-d9 | 2260669-52-9 | 99.0% | 548.97 | 1 MG
CER10-d9 is a deuterium-labeled version of CER10, designed for research purposes. It is explicitly stated that it is not for sale to patients. This compound is offered in solid form and presents as a white to off-white substance.
- Tracer application
- Internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS
- Deuterium labeling incorporates stable heavy isotopes of hydrogen
- Availability in multiple quantities
- Quality boasts a purity of 99.0%
Medchemexpress LLC Sodium propionate-d5 | 202529-18-8 | 99.9% | 25 MG
Sodium propionate-d5 is the deuterium-labeled version of Sodium propionate, which is an orally active short-chain fatty acid. It is produced by intestinal bacteria from dietary fiber metabolism. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, reduces COX-2 expression and NO production, and induces Apoptosis and Autophagy. It also reduces HSV-1-induced keratitis and has anticancer effects against glioblastoma. Additionally, it exhibits neuroprotective, antioxidant, and anti-inflammatory activities, making it useful in research for spinal cord injury and Alzheimer's disease.
- Deuterium labeled compound.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.